Detection of antitrophoblast antibodies in the sera of patients with anticardiolipin antibodies and fetal loss

Detection of antitrophoblast antibodies in the sera of patients with anticardiolipin antibodies and fetal loss.

Women with anticardiolipin antibodies (ACLA) are at increased risk for fetal loss. One potential explanation for this outcome is that sera from these individuals contain antibodies reactive with trophoblast cells, which are involved in the establishment of the uteroplacental vasculature and maintenance of placental blood fluidity. To examine this hypothesis, we compared the incidence of trophob...

Anticardiolipin and Antiphospholipid Antibodies in Iraqi Patients with Angina Pectoris

Lupus anticoagulant, anticardiolipin antibodies, fetal loss, and systemic lupus erythematosus.

UPUS ANTICOAGULANTS (LA) and anticardioL lipin (ACL) antibodies (ACLA) belong to a heterogenous group of antibodies directed against negatively charged pho~pholipids.l-~ However, more recent studies would suggest that these antibodies are directed to epitopes of other proteins that are complexed with negatively charged phospholipid~>-~ Although antiphospholipid antibodies are frequently found i...

Anticardiolipin and Antibeta2glycoproteinI Antibodies in Patients with Hepatitis B and C Infections

Background: The clinical significance of antiphospholipid antibodies in patients with chronic hepatitis C virus (HCV) and some other viral infections is controversial. Objective: To study the prevalence of anticardiolipin antibody (ACLA) and antibeta2glycoproteinI antibody (antibeta2GPI antibody) in HCV and hepatitis B virus (HBV) infected patients and its association with liver clinical parame...

Anticardiolipin antibodies in the sera of patients with diagnosed chronic fatigue syndrome.

Examination of anticardiolipin antibodies (ACAs) in the sera of patients clinically diagnosed with chronic fatigue syndrome (CFS) using an enzyme-linked immunoassay procedure demonstrated the presence of immunoglobulin M isotypes in 95% of CFS serum samples tested. The presence of immunoglobulin G and immunoglobulin A isotypes were also detected in a subset of the samples. Future studies will f...